Metastasis of gestational trophoblastic neoplasia to the spinal canal: a case report

Abstract

Background: Spinal canal metastasis secondary to gestational trophoblastic neoplasia (GTN) is a rare condition.

Case: A 21-year-old female presented with symptoms of cauda equina compression by an extradural metastasis from GTN. The patient received multiagent chemotherapy combined with intrathecal methotrexate administration. Her neurologic symptoms improved remarkably after the cessation of chemotherapy. During the 21-month follow-up period, she was asymptomatic and has shown overall improvement in well-being.

Conclusion: Spinal canal metastasis of GTN is a possibility that must be considered in young women with a history of hydatidiform mole who have neurologic symptoms or signs, which were improved completely by chemotherapy alone in this case.