Objective: We evaluated serum chitotriosidase activity in patients with Wegener's granulomatosis (WG) and compared the values to controls.
Design and methods: We used a standard fluorometric assay to measure chitotriosidase enzyme activity.
Results: Serum chitotriosidase enzyme activity levels were higher in WG patients. We found no association between clinical disease activity and chitotriosidase enzyme activity.
Conclusions: Serum chitotriosidase enzyme activity has limited utility as a biomarker in WG patients.
Published by Elsevier Inc.