Warfarin-induced skin necrosis

South Med J. 2010 Jan;103(1):74-5. doi: 10.1097/SMJ.0b013e3181c47dcf.

Abstract

There is a lack of guidelines regarding the selection of patients who need intravenous heparin, duration of intravenous heparin, and future use of warfarin in prevention and treatment of warfarin-induced skin necrosis. This case report emphasizes the challenges in dealing with vitamin K antagonists (VKA) therapy.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anticoagulants / adverse effects*
  • Combined Modality Therapy
  • Drug Administration Schedule
  • Heparin / administration & dosage
  • Humans
  • Male
  • Necrosis / chemically induced
  • Skin / pathology*
  • Systemic Inflammatory Response Syndrome / complications*
  • Thrombophilia / complications
  • Vitamin K Deficiency / chemically induced*
  • Vitamin K Deficiency / complications
  • Warfarin / adverse effects*

Substances

  • Anticoagulants
  • Warfarin
  • Heparin