SNR-optimized myocardial perfusion imaging using parallel acquisition for effective density-weighted saturation recovery imaging

Magn Reson Imaging. 2010 Apr;28(3):341-50. doi: 10.1016/j.mri.2009.11.007. Epub 2010 Jan 21.

Abstract

The concept of density-weighted imaging and parallel acquisition for effective density-weighted (PLANED) imaging was transferred to saturation recovery (SR) sequences, in order to increase the SNR in first-pass myocardial perfusion imaging. Filtering in combination with density-weighted imaging allows SNR-optimized data weighting and the free choice of the corresponding spatial response function (SRF) simultaneously. This method was evaluated in simulations and applied successfully to phantom and in vivo first-pass myocardial perfusion studies. Unfiltered, Cartesian sampled images were compared to images acquired with SR-PLANED, which has been adjusted to result in an identical SRF as the Cartesian imaging. SNR-optimized SR-PLANED imaging improved the SNR up to 15% without changing acquisition time, the SRF or the field of view (FOV). The presented method provides high image quality and optimized SNR for first-pass myocardial perfusion imaging.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Humans
  • Image Enhancement / methods*
  • Image Interpretation, Computer-Assisted / methods*
  • Magnetic Resonance Angiography / methods*
  • Myocardial Perfusion Imaging / methods*
  • Phantoms, Imaging
  • Reproducibility of Results
  • Sensitivity and Specificity