Two unusual cases of severe soft tissue infection caused by Streptococcus dysgalactiae subsp. equisimilis

J Clin Microbiol. 2010 Apr;48(4):1484-7. doi: 10.1128/JCM.01737-09. Epub 2010 Feb 10.

Abstract

We present two cases of invasive infection caused by Streptococcus dysgalactiae subsp. equisimilis, one that showed rapidly developing necrotizing fasciitis in a previously healthy man and one that showed severe cellulitis and septic shock even though the bacterium possessed a mutated emm gene, predicted to encode a truncated M protein.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Antigens, Bacterial / genetics
  • Bacterial Outer Membrane Proteins / genetics
  • Bacterial Proteins / genetics
  • Carrier Proteins / genetics
  • Cellulitis / complications
  • Cellulitis / microbiology
  • DNA, Bacterial / chemistry
  • DNA, Bacterial / genetics
  • Fasciitis, Necrotizing / microbiology
  • Humans
  • Male
  • Middle Aged
  • Molecular Sequence Data
  • Mutation
  • Sequence Analysis, DNA
  • Sequence Deletion
  • Shock, Septic / microbiology
  • Soft Tissue Infections / microbiology*
  • Streptococcal Infections / diagnosis*
  • Streptococcal Infections / microbiology
  • Streptococcus / classification*
  • Streptococcus / genetics
  • Streptococcus / isolation & purification*
  • Virulence Factors / genetics

Substances

  • Antigens, Bacterial
  • Bacterial Outer Membrane Proteins
  • Bacterial Proteins
  • Carrier Proteins
  • DNA, Bacterial
  • Virulence Factors
  • streptococcal M protein

Associated data

  • GENBANK/FJ531857
  • GENBANK/GQ390354
  • GENBANK/GQ390355
  • GENBANK/GQ390356
  • GENBANK/GQ390357
  • GENBANK/GQ845001