Efficacy of ivabradine in a case of inappropriate sinus tachycardia and ventricular dysfunction

J Cardiovasc Electrophysiol. 2010 Jul;21(7):815-7. doi: 10.1111/j.1540-8167.2009.01699.x. Epub 2010 Mar 5.

Abstract

We present a case of a 49-year-old man with inappropriate sinus tachycardia and ventricular dysfunction. The conventional treatment (ace-inhibitor and beta-blockers) was not well tolerated by the patient, so Ivabradine, a specific inhibitor of If current in the sinus node, was started. After 3 months of using this medication, we observed an improvement of ejection fraction and quality of life.

Publication types

  • Case Reports

MeSH terms

  • Anti-Arrhythmia Agents / therapeutic use*
  • Benzazepines / therapeutic use*
  • Electrocardiography
  • Heart Rate / drug effects
  • Humans
  • Ivabradine
  • Male
  • Middle Aged
  • Quality of Life
  • Stroke Volume / drug effects
  • Tachycardia, Sinus / complications
  • Tachycardia, Sinus / drug therapy*
  • Tachycardia, Sinus / physiopathology
  • Time Factors
  • Treatment Outcome
  • Ventricular Dysfunction, Left / drug therapy*
  • Ventricular Dysfunction, Left / etiology
  • Ventricular Dysfunction, Left / physiopathology
  • Ventricular Function, Left / drug effects

Substances

  • Anti-Arrhythmia Agents
  • Benzazepines
  • Ivabradine