Abstract
Certain secreted proteins bypass the canonical exit pathway from cells. Two studies now shed light on the unconventional secretion route taken by the yeast acyl-coenzyme A-binding protein: this protein is sequestered into autophagic vesicles that are re-routed to the plasma membrane where their content is released to the extracellular space.
(c) 2010 Elsevier Ltd. All rights reserved.
MeSH terms
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Autophagy / physiology
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Carrier Proteins / metabolism
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Cell Membrane / physiology
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Diazepam Binding Inhibitor / metabolism*
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Saccharomyces cerevisiae / physiology
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Saccharomyces cerevisiae Proteins / metabolism
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Secretory Pathway / physiology*
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Secretory Vesicles / physiology*
Substances
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ACB1 protein, S cerevisiae
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Carrier Proteins
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Diazepam Binding Inhibitor
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Saccharomyces cerevisiae Proteins