The latent structure of alcohol use pathology in an epidemiological sample

J Psychiatr Res. 2011 Feb;45(2):225-33. doi: 10.1016/j.jpsychires.2010.06.001. Epub 2010 Jul 7.

Abstract

Whether alcohol use pathology is more accurately conceptualized as a categorical construct, or as existing along a dimension remains an open question. Previous investigations of the latent structure of alcohol use pathology have yielded mixed results. The present study used a sample (N = 43,093) drawn from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) of the National Institute on Alcohol Abuse and Alcoholism. A factor analysis of items drawn from the Alcohol Consumption, Alcohol Abuse/Dependence (Alcohol Experiences), and Alcohol Treatment Utilization sections of the NESARC yielded three factors, labeled Functional Disturbance, Tolerance, and Frequency, which were used as indicators in a series of taxometric analyses. These analyses converged on a low base rate alcohol pathology taxon. The relevance of these findings for the diagnosis, etiology, further research, and treatment of alcohol use disorders is discussed.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Alcohol-Related Disorders / epidemiology*
  • Alcohol-Related Disorders / pathology*
  • Factor Analysis, Statistical
  • Female
  • Health Surveys
  • Humans
  • Male
  • Middle Aged
  • National Institute on Alcohol Abuse and Alcoholism (U.S.) / statistics & numerical data
  • Reproducibility of Results
  • United States / epidemiology
  • Young Adult