One-pot syntheses of chromeno[3,4-c]pyrrole-3,4-diones via Ugi-4CR and intramolecular Michael addition

Chao Che; Song Li; Xianlong Jiang; Junmin Quan; Shuo Lin; Zhen Yang

doi:10.1021/ol1020477

One-pot syntheses of chromeno[3,4-c]pyrrole-3,4-diones via Ugi-4CR and intramolecular Michael addition

Org Lett. 2010 Oct 15;12(20):4682-5. doi: 10.1021/ol1020477.

Authors

Chao Che¹, Song Li, Xianlong Jiang, Junmin Quan, Shuo Lin, Zhen Yang

Affiliation

¹ Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, China. chec@szpku.edu.cn

PMID: 20857977
DOI: 10.1021/ol1020477

Abstract

One-pot and diastereoselective syntheses of diverse chromeno[3,4-c]pyrrole-3,4-diones from readily available starting materials were achieved via sequential Ugi-4CR and intramolecular Michael addition.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Benzopyrans / chemistry*
Crystallography, X-Ray
Models, Molecular
Molecular Structure
Pyrroles / chemical synthesis*
Stereoisomerism

Substances

Benzopyrans
Pyrroles