How to manage the patient with early-age-of-onset (<50 years) colorectal cancer?

Jennifer Liang; James Church

doi:10.1016/j.soc.2010.07.007

How to manage the patient with early-age-of-onset (<50 years) colorectal cancer?

Surg Oncol Clin N Am. 2010 Oct;19(4):725-31. doi: 10.1016/j.soc.2010.07.007.

Authors

Jennifer Liang¹, James Church

Affiliation

¹ Department of Colorectal Surgery, Digestive Diseases Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH, USA.

PMID: 20883949
DOI: 10.1016/j.soc.2010.07.007

Abstract

Colorectal cancer rarely occurs before the age of 50. When it does, it is often advanced and aggressive. There may be predisposing genetic and immune factors that lead to its origin. Genetic counseling is indicated for all patients younger than 50 with colorectal cancer. Before surgery, the tumor and the patient must be evaluated as fully as possible, so that optimal treatment, follow-up, and surveillance are used.

Publication types

Review

MeSH terms

Adult
Age of Onset
Colorectal Neoplasms / genetics*
Colorectal Neoplasms / pathology*
Colorectal Neoplasms / therapy*
Genetic Predisposition to Disease
Humans
Middle Aged