Medulloblastoma variants and survival at a children's hospital

Fetal Pediatr Pathol. 2011;30(1):53-9. doi: 10.3109/15513815.2010.505627.

Abstract

Our 25 year experience with 35 medulloblastomas included classic (NOS) 22 (63%), anaplastic (ANA) 5(14%), desmoplastic (DES) 4(11%), excessive nodularity (EN) 3(9%), and large cell (LC) 1(3%). Overall 5, 10, and 15 year survivals were .6631, .5851, and .5051. Those under 3 years at diagnosis had an overall 2 year survival of .4379. Two survived 17(NOS) and 19 (EN) years. In the 26 children 3 years or older, late deaths occurred at 8, 8, and 14 years (5, 10, 15 year survivals .7375, .6392, .5114). Because late deaths occur; continued follow-up of these children is required.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Cerebellar Neoplasms / mortality
  • Cerebellar Neoplasms / pathology*
  • Cerebellar Neoplasms / therapy
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Louisiana / epidemiology
  • Male
  • Medulloblastoma / mortality
  • Medulloblastoma / pathology*
  • Medulloblastoma / therapy
  • Registries
  • Survival Rate