Objective: The aim of this article is to discuss the relation between serum uric acid and prehypertension, and to evaluate the influence of age, obesity, fasting plasma glucose (FPG) and lipids in Chinese adults.
Methods: All the 14 451 non-hypertensive samples were analyzed for blood pressure, body mass index (BMI), FPG, lipids and serum uric acid.
Results: The serum uric acid levels were stratified by quintiles, after adjustment for relevant factors, OR values of prehypertension increased with the elevated uric acid levels. Serum uric acid level was 200 - 380 µmol/L, it had a linear relationship with the risk of prehypertension, 200 µmol/L as a turning point for this linear relationship, FPG could affect their correlation (P < 0.0001).
Conclusions: Serum uric acid was associated with prehypertension, independent of metabolic risk factors. The associations were not significant in old individuals. FPG may modify the associations.