Fluvoxamine treatment of coincident autistic disorder and obsessive-compulsive disorder: a case report

J Autism Dev Disord. 1990 Dec;20(4):537-43. doi: 10.1007/BF02216058.

Abstract

This is a single-case report of fluvoxamine treatment of comorbid autistic disorder (AD) and obsessive-compulsive disorder (OCD). Psychological, neuroanatomical, and neurochemical parallels are drawn between AD and OCD. The implications of this case of coincident AD and OCD, as well as the response to fluvoxamine, are discussed with respect to nosology, pathophysiology, and treatment of these disorders.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Autistic Disorder / complications
  • Autistic Disorder / drug therapy*
  • Autistic Disorder / psychology
  • Dose-Response Relationship, Drug
  • Fluvoxamine
  • Humans
  • Male
  • Neurocognitive Disorders / complications
  • Neurocognitive Disorders / drug therapy
  • Neurocognitive Disorders / psychology
  • Obsessive-Compulsive Disorder / complications
  • Obsessive-Compulsive Disorder / drug therapy*
  • Obsessive-Compulsive Disorder / psychology
  • Oximes / therapeutic use*
  • Serotonin Antagonists*

Substances

  • Oximes
  • Serotonin Antagonists
  • Fluvoxamine