Neurocognitive functioning and suicidality in schizophrenia spectrum disorders

Compr Psychiatry. 2011 Mar-Apr;52(2):156-63. doi: 10.1016/j.comppsych.2010.06.001. Epub 2010 Jul 29.

Abstract

Objective: The aim of this study was to investigate whether suicide attempters had higher IQ, better executive functioning, or were more impulsive as measured by neuropsychological tests than non-attempters in a group of patients with schizophrenia spectrum disorders.

Method: One hundred seventy-four patients with schizophrenia spectrum disorders were assessed with a clinical interview for diagnosis, suicidality, symptoms and function, and underwent an extensive neurocognitive test battery.

Results: There were no statistically significant differences in any neurocognitive domains between lifetime suicide attempters and non-attempters, or between patients with different rates of suicide attempts. Currently suicidal patients were significantly more impulsive (had poorer inhibitory control) than currently non-suicidal patients, but this difference was mediated by positive psychotic symptoms.

Conclusion: The findings indicate that among patients with schizophrenia spectrum disorders, there are no significant differences in IQ or neurocognitive functioning between suicide attempters and non-attempters.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Attention
  • Cognition*
  • Diagnostic and Statistical Manual of Mental Disorders
  • Female
  • Humans
  • Interview, Psychological
  • Male
  • Memory
  • Middle Aged
  • Neuropsychological Tests
  • Psychotic Disorders / diagnosis
  • Psychotic Disorders / psychology*
  • Schizophrenia / diagnosis
  • Schizophrenic Psychology*
  • Severity of Illness Index
  • Suicidal Ideation*
  • Suicide, Attempted / psychology*