Ectopic pregnancy after levonorgestrel emergency contraception

Contraception. 2011 Mar;83(3):281-3. doi: 10.1016/j.contraception.2010.08.008. Epub 2010 Oct 29.

Abstract

Background: Although the possibility of ectopic pregnancy after intake of levonorgestrel (LNG) as an emergency contraceptive (EE) pill is well-known, the causality has not been well established.

Case: A 27-year-old nulliparous woman with regular menstrual periods took 1.5-mg LNG EE midcyclic 5 h after an unprotected intercourse. She had prolonged vaginal bleeding at the expected time. She consulted the general practitioner because of continuous vaginal bleeding for 4 weeks and lower abdominal pain. The pregnancy test was positive, and her symptoms and clinical findings suggested an ectopic pregnancy. At emergency surgery, she was found to have a left tubal pregnancy.

Conclusion: The possible role of 1.5-mg LNG EE in causing ectopic pregnancy is discussed. A high serum LNG concentration decreases ciliary activity and tube motility, but further epidemiological studies are necessary to establish the risk of ectopic pregnancy following intake of LNG EE.

Publication types

  • Case Reports

MeSH terms

  • Contraception, Postcoital / adverse effects*
  • Contraception, Postcoital / methods*
  • Contraceptives, Postcoital, Synthetic*
  • Female
  • Humans
  • Levonorgestrel*
  • Pregnancy
  • Pregnancy, Tubal / etiology*
  • Pregnancy, Tubal / surgery

Substances

  • Contraceptives, Postcoital, Synthetic
  • Levonorgestrel