Update: metabolic and cardiovascular consequences of bariatric surgery

Endocrinol Metab Clin North Am. 2011 Mar;40(1):81-96, viii. doi: 10.1016/j.ecl.2010.12.009.

Abstract

Obesity is a disease state with polygenic inheritance, the phenotypic penetrance of which has been greatly expanded by the attributes of modern civilization. More than two-thirds of obese persons have comorbidities, many of which are characteristic of cardiometabolic risk syndrome (CMRS) in addition to other life-quality-reducing complaints. The CMRS is associated with increased cardiovascular events and mortality. Individuals with a body mass index greater than 35 infrequently achieve or maintain weight loss adequate to resolve these metabolic and anatomic issues by lifestyle or pharmacologic strategies. Data suggest that some of these patients may be better served by bariatric surgery.

Publication types

  • Review

MeSH terms

  • Bariatric Surgery / adverse effects*
  • Bariatric Surgery / rehabilitation
  • Cardiovascular Diseases / epidemiology
  • Cardiovascular Diseases / etiology*
  • Cardiovascular System / physiopathology
  • Endocrinology / trends
  • Humans
  • Metabolic Diseases / epidemiology
  • Metabolic Diseases / etiology*
  • Obesity, Morbid / epidemiology
  • Obesity, Morbid / metabolism
  • Obesity, Morbid / physiopathology
  • Obesity, Morbid / surgery*
  • Risk Factors
  • Syndrome
  • Weight Loss / physiology