Millet-porridge with Artemisia annua as first aid for African children with malaria?

J Altern Complement Med. 2011 Apr;17(4):371-3. doi: 10.1089/acm.2010.0252. Epub 2011 Mar 28.

Abstract

Objectives: In a few malaria-endemic countries with high disease prevalence, especially in children, and local cultivation of Artemisia annua, the availability of recommended malaria medicines is scant. New sources of treatment could be used, drawing from traditional medicine.

Methods: A popular African millet-porridge was prepared by adding dried, sieved leaves of Artemisia annua. Artemisinin concentrations were detected by high-performance liquid chromatography-mass spectrometry.

Results: The artemisinin content of the porridge is stable and the concentration is maintained. The taste of the porridge is palatable.

Conclusions: Further research is needed before proposing the millet-porridge artemisinin formulation, but such an affordable therapy could be an option in the near future (also) for children living in poor areas where access to effective antimalarial drugs is precluded.

MeSH terms

  • Antimalarials / analysis*
  • Antimalarials / therapeutic use
  • Artemisia annua / chemistry*
  • Artemisinins / analysis*
  • Artemisinins / therapeutic use
  • Child
  • Chromatography, High Pressure Liquid
  • Edible Grain*
  • Food, Fortified
  • Humans
  • Malaria / drug therapy*
  • Panicum
  • Phytotherapy*
  • Plant Leaves / chemistry
  • Plant Preparations / chemistry*
  • Plant Preparations / therapeutic use
  • Taste

Substances

  • Antimalarials
  • Artemisinins
  • Plant Preparations
  • artemisinin