A potential case of peduncular hallucinosis treated successfully with olanzapine

Clin Schizophr Relat Psychoses. 2011 Apr;5(1):50-3. doi: 10.3371/CSRP.5.1.7.

Abstract

Visual hallucinations have a differential diagnosis, both psychiatric and nonpsychiatric in nature. Described first by Lhermitte, peduncular hallucinosis is an uncommon etiology of visual hallucinations (VH). Typically, the offending lesion is vascular in origin and occurs at the level of the midbrain, thalamus, or rostral brainstem. Interestingly, the origin of the VH in our patient's case could have been either/both from an ischemic insult at the midbrain or compression of the brainstem due to aneurism. While evidence for treatment is scarce, we present a posited case of peduncular hallucinosis treated successfully with olanzapine.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antipsychotic Agents / therapeutic use*
  • Benzodiazepines / therapeutic use*
  • Cerebral Infarction / complications*
  • Cerebral Infarction / diagnosis
  • Cerebral Infarction / drug therapy
  • Cerebral Infarction / psychology
  • Female
  • Follow-Up Studies
  • Hallucinations / diagnosis
  • Hallucinations / drug therapy*
  • Hallucinations / psychology
  • Humans
  • Intracranial Aneurysm / complications*
  • Intracranial Aneurysm / diagnosis
  • Intracranial Aneurysm / psychology
  • Intracranial Aneurysm / surgery*
  • Magnetic Resonance Angiography
  • Magnetic Resonance Imaging
  • Mental Status Schedule
  • Neurocognitive Disorders / diagnosis
  • Neurocognitive Disorders / drug therapy*
  • Neurocognitive Disorders / psychology
  • Neurologic Examination
  • Olanzapine
  • Postoperative Complications / diagnosis
  • Postoperative Complications / drug therapy*
  • Postoperative Complications / psychology
  • Schizophrenia / diagnosis
  • Schizophrenia / drug therapy*
  • Schizophrenic Psychology*
  • Tegmentum Mesencephali / blood supply*
  • Tegmentum Mesencephali / pathology

Substances

  • Antipsychotic Agents
  • Benzodiazepines
  • Olanzapine