Abstract
Nasal polyps (NPs) represent a common clinical end point for a myriad of inflammatory disease processes involving the paranasal sinuses. Chronic rhinosinusitis is the most common cause for NPs, but not all NPs are created equally. This article outlines the current understanding of pathogenesis in nasal polyposis and discusses the implications on therapy.
Copyright © 2011 Elsevier Inc. All rights reserved.
MeSH terms
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Asthma, Aspirin-Induced / complications
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Chronic Disease
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Cystic Fibrosis / complications
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Cytokines / physiology
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Enterotoxins / physiology
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Eosinophilia / complications
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Humans
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Nasal Polyps / etiology*
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Nasal Polyps / therapy*
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Rhinitis / complications
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Sinusitis / complications
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Staphylococcus aureus / metabolism
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T-Lymphocytes / physiology
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Transforming Growth Factor beta1 / physiology
Substances
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Cytokines
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Enterotoxins
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Transforming Growth Factor beta1