Age does not influence the effect of embryo fragmentation on successful blastocyst development

Diana H Wu; Kasey Reynolds; Rose Maxwell; Steven R Lindheim; Mira Aubuchon; Michael A Thomas

doi:10.1016/j.fertnstert.2011.05.024

Age does not influence the effect of embryo fragmentation on successful blastocyst development

Fertil Steril. 2011 Jun 30;95(8):2778-80. doi: 10.1016/j.fertnstert.2011.05.024. Epub 2011 Jun 8.

Authors

Diana H Wu¹, Kasey Reynolds, Rose Maxwell, Steven R Lindheim, Mira Aubuchon, Michael A Thomas

Affiliation

¹ Center for Reproductive Health, University of Cincinnati Academic Health Center, Cincinnati, Ohio 45219, USA. dhwu88@gmail.com

PMID: 21641595
DOI: 10.1016/j.fertnstert.2011.05.024

Abstract

We evaluated the rate of blastocyst development in day 3 embryos with appropriate cellular division and investigated whether maternal age modified the effect of embryo fragmentation on blastulation. Our data showed a significant negative correlation between the degree of embryo fragmentation and rate of blastocyst development, but age did not exert an effect on the degree of fragmentation in embryos with appropriate cleaving status, nor did it modify the significant effect embryo fragmentation had on blastocyst formation.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Blastocyst / pathology*
Chi-Square Distribution
Cleavage Stage, Ovum / pathology*
Embryo Culture Techniques
Embryonic Development
Female
Fertilization in Vitro*
Humans
Maternal Age*
Ohio
Retrospective Studies
Risk Assessment
Risk Factors
Time Factors
Young Adult