Is there any impact of cognitive remediation on an ecological test in schizophrenia?

Cogn Neuropsychiatry. 2012;17(1):19-35. doi: 10.1080/13546805.2011.564512. Epub 2011 Jun 28.

Abstract

Introduction: Cognitive deficits are commonly reported in schizophrenia and have a significant impact on the daily life of patients and on their social and work inclusion. Cognitive remediation therapies (CRT) may enhance the capabilities of schizophrenia patients. Although social and work integration is the ultimate goal of CRT, previous studies have failed to carry out a detailed assessment of the effects on everyday life.

Methods: Fifty-nine schizophrenia patients were randomised into two groups (remediation or usual treatment) to test the effects of a new remediation programme, which included both rehearsal and strategy learning, on cognitive functions. An ecological test was used to evaluate its transfer to daily living skills.

Results: Cognitive improvements are revealed in CRT patients, mainly in memory and executive functions. Patients showing some deficiencies to perform the ecological test had better scores after the CRT. Moreover, they significantly improve their social activity scores.

Conclusions: CRT would facilitate mental load monitoring by enhancing or reallocating cognitive resources, facilitating the patient's organisation and autonomy. The rehearsal learning approach improves the ability to carry out automatic operations that are less demanding in terms of cognitive resources, thereby increasing the resources available for acquisition and efficient use of strategies provided during the strategy learning approach.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antipsychotic Agents / therapeutic use
  • Attention / physiology
  • Cognition / physiology*
  • Cognition Disorders / etiology
  • Cognition Disorders / psychology
  • Cognitive Behavioral Therapy / methods*
  • Diagnostic and Statistical Manual of Mental Disorders
  • Educational Status
  • Executive Function
  • Female
  • Humans
  • Intelligence Tests
  • Learning / physiology
  • Male
  • Neuropsychological Tests
  • Schizophrenia / diagnosis*
  • Schizophrenia / rehabilitation
  • Schizophrenia / therapy*
  • Schizophrenic Psychology*
  • Social Behavior
  • Therapy, Computer-Assisted

Substances

  • Antipsychotic Agents