Life-space mobility is associated with frequency of hospitalization in adults with cystic fibrosis

Clin Respir J. 2011 Oct;5(4):245-51. doi: 10.1111/j.1752-699X.2010.00225.x. Epub 2010 Oct 1.

Abstract

Introduction and objectives: The Life-Space Assessment can be used to measure a patient's level of mobility. This study evaluated the relationship between life-space mobility and frequency of hospitalization in the previous year and other clinical markers of health among adults with cystic fibrosis (CF).

Methods: The Life-Space Assessment was administered to ambulatory adults with CF in clinic or by telephone. Life-space mobility was correlated with the most recent forced expiratory volume in one second as a percent of the predicted value (FEV(1) % predicted), body mass index (BMI) and number of hospitalizations in the previous year.

Results: Forty-eight subjects completed the Life-Space Assessment. Subjects had a life-space score of 88 ± 26, FEV(1) % predicted of 66% ± 26% and BMI of 22.5 ± 3.3. There was a statistically significant negative linear correlation between the number of times a subject was hospitalized in the previous year and life-space mobility (P = 0.001, R(2) = 0.20). This association was independent of FEV(1) % predicted and BMI.

Conclusion: The life-space mobility score is associated with frequency of hospitalization in adults with CF. A prospective study should be undertaken to assess the ability of the Life-Space Assessment to predict hospitalization and other outcomes in adults with CF.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Body Mass Index
  • Cystic Fibrosis / physiopathology*
  • Cystic Fibrosis / therapy
  • Female
  • Forced Expiratory Volume
  • Hospitalization*
  • Humans
  • Male
  • Quality of Life
  • Surveys and Questionnaires
  • Walking*