No abstract available
Publication types
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Letter
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Research Support, Non-U.S. Gov't
MeSH terms
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Apoptosis / drug effects
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Biomarkers, Tumor / genetics*
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Bone Neoplasms / drug therapy
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Bone Neoplasms / genetics*
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Bone Neoplasms / pathology
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Cell Cycle Proteins
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Gene Amplification / genetics*
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Gene Dosage / genetics
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Humans
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Imidazoles / pharmacology
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Imidazoles / therapeutic use
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Mutation / genetics
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Nuclear Proteins / genetics*
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Osteosarcoma / drug therapy
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Osteosarcoma / genetics*
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Osteosarcoma / pathology
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Piperazines / pharmacology
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Piperazines / therapeutic use
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Proto-Oncogene Proteins / genetics*
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Proto-Oncogene Proteins c-mdm2 / genetics*
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Retrospective Studies
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Tumor Suppressor Protein p53 / genetics
Substances
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Biomarkers, Tumor
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Cell Cycle Proteins
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Imidazoles
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MDM4 protein, human
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Nuclear Proteins
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Piperazines
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Proto-Oncogene Proteins
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Tumor Suppressor Protein p53
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nutlin 3
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MDM2 protein, human
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Proto-Oncogene Proteins c-mdm2