[Incidence of secondary tumors following cervical neoplasia in Saarland 1968-1987]

Geburtshilfe Frauenheilkd. 1990 Aug;50(8):614-8. doi: 10.1055/s-2008-1026311.
[Article in German]

Abstract

In 4468 patients diagnosed with invasive cancer or carcinoma in situ of the uterine cervix in Saarland/W-Germany in 1968-1987, 149 secondary cancers were observed compared to 150.6 which would have been expected had the same risk prevailed as in the general population (SMR = 0.99, 95% confidence interval 0.84-1.17). There were, however, substantial differences between the relative risks for specific cancer sites. For example, the risk of breast cancer was clearly lower than in the general population (SMR = 0.62, 95% confidence interval 0.43-0.88), while the risk of cancer of the urinary bladder was significantly increased (SMR = 2.88, 95% confidence interval 1.53-4.93). The results are consistent with findings from other countries, with current knowledge of risk factor profiles of different malignancies and with hypotheses on possible side effects of radiotherapy.

Publication types

  • English Abstract

MeSH terms

  • Carcinoma in Situ / mortality*
  • Carcinoma in Situ / radiotherapy
  • Cause of Death
  • Cross-Sectional Studies
  • Female
  • Germany, West / epidemiology
  • Humans
  • Incidence
  • Neoplasms, Multiple Primary / mortality*
  • Neoplasms, Radiation-Induced / mortality
  • Registries*
  • Uterine Cervical Neoplasms / mortality*
  • Uterine Cervical Neoplasms / radiotherapy