Hyperprolactinaemia and the empty sella

J Clin Neurosci. 2012 Apr;19(4):605-6. doi: 10.1016/j.jocn.2011.06.025. Epub 2012 Jan 14.

Abstract

Hyperprolactinaemia is an endocrine abnormality seen not infrequently in the population with empty sella; a radiological and anatomical diagnosis of a deformed and enlarged sella turcica. Often there is no associated pathology within the pituitary gland itself, lending to the hypothesis that the empty sella syndrome per se has a yet-to-be defined role in hyperprolactinemia. We report a patient who presented initially with non-specific symptoms of meningeal irritation and viral illness on a long background of galactorrhoea. The patient demonstrated elevated serum prolactin, and a diagnosis of empty sella was made on the basis of MRI findings.

Publication types

  • Case Reports

MeSH terms

  • Antidepressive Agents / therapeutic use
  • Depression / complications
  • Depression / drug therapy
  • Empty Sella Syndrome / complications*
  • Female
  • Galactorrhea / etiology
  • Humans
  • Hyperprolactinemia / complications*
  • Magnetic Resonance Imaging
  • Middle Aged
  • Tomography, X-Ray Computed

Substances

  • Antidepressive Agents