Metastatic hepatocellular carcinoma presenting as facial nerve palsy and facial pain

Korean J Hepatol. 2011 Dec;17(4):319-22. doi: 10.3350/kjhep.2011.17.4.319.

Abstract

Facial nerve palsy due to temporal bone metastasis of hepatocellular carcinoma (HCC) has rarely been reported. We experienced a rare case of temporal bone metastasis of HCC that initially presented as facial nerve palsy and was diagnosed by surgical biopsy. This patient also discovered for the first time that he had chronic hepatitis B and C infections due to this facial nerve palsy. Radiation therapy greatly relieved the facial pain and facial nerve palsy. This report suggests that hepatologists should consider metastatic HCC as a rare but possible cause of new-onset cranial neuropathy in patients with chronic viral hepatitis.

Publication types

  • Case Reports

MeSH terms

  • Carcinoma, Hepatocellular / complications
  • Carcinoma, Hepatocellular / pathology*
  • Facial Nerve Diseases / diagnosis
  • Facial Nerve Diseases / etiology
  • Facial Pain / etiology
  • Facial Paralysis / diagnosis
  • Facial Paralysis / etiology
  • Hepatitis B, Chronic / diagnosis
  • Hepatitis C, Chronic / diagnosis
  • Humans
  • Immunohistochemistry
  • Liver Neoplasms / complications
  • Liver Neoplasms / pathology*
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Positron-Emission Tomography
  • Skull Neoplasms / diagnosis*
  • Skull Neoplasms / pathology
  • Skull Neoplasms / secondary
  • Tomography, X-Ray Computed