GOHTAM: a website for 'Genomic Origin of Horizontal Transfers, Alignment and Metagenomics'

Bioinformatics. 2012 May 1;28(9):1270-1. doi: 10.1093/bioinformatics/bts118. Epub 2012 Mar 15.

Abstract

Motivation: This website allows the detection of horizontal transfers based on a combination of parametric methods and proposes an origin by researching neighbors in a bank of genomic signatures. This bank is also used to research an origin to DNA fragments from metagenomics studies.

Results: Different services are provided like the possibility of inferring a phylogenetic tree with sequence signatures or comparing two genomes and displaying the rearrangements that happened since their separation.

Availability and implementation: http://gohtam.rpbs.univ-paris-diderot.fr/

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacteria / classification
  • Bacteria / genetics
  • Gene Transfer, Horizontal*
  • Genome
  • Genome, Bacterial
  • Metagenomics / methods*
  • Phylogeny*
  • Sequence Alignment / methods
  • Sequence Analysis, DNA / methods