Combined ERCP and EUS in one session is safe in elderly patients when compared to non-elderly patients: outcomes in 206 combined procedures

Dig Dis Sci. 2012 Jul;57(7):1949-53. doi: 10.1007/s10620-012-2135-2. Epub 2012 Mar 28.

Abstract

Aims: Combined ERCP/EUS is becoming common. Combined procedures are frequently performed in elderly patients. We hypothesized that combined ERCP/EUS is equally safe in elderly patients when compared to non-elderly patients.

Methods: This was a retrospective single-center study comparing outcomes in elderly and non-elderly patients undergoing combined ERCP/EUS.

Results: A total of 206 patients were included. Mean age was 65 years (M:F 113:93); 99 were <65 years and 107 were >65. Indications included: jaundice (51%), abnormal imaging (17%), pancreatic tumor (11%), abdominal pain (5%), stent placement/change (5%), acute or chronic pancreatitis (5%), other (6%). Fine needle aspiration was performed in 134 (65%) procedures. Malignancy was identified in 142/206 (69%) patients. Mean Charlson Comorbidity Index (CCI) was 7.5 (range 0-22). Among patients <65 years old there were no immediate adverse events. Long-term adverse events in patients <65 (within 30 days) included cholangitis (1), increasing abdominal pain (4), post-ERCP pancreatitis (3), nausea/vomiting (1), increasing fatigue (1), and increasing jaundice (1). A subgroup analysis among geriatric patients (>65) was performed. Mean CCI was 8.2 (range 0-22). There was one immediate adverse event of non-sustained ventricular tachycardia in a 76-year old. Long-term adverse events included increasing fatigue (1), nausea/vomiting (2), increasing abdominal pain (2), urosepsis (1), fever (2) and dehydration (1). There were no statistically significant differences in outcomes in elderly compared to non-elderly patients. Elderly patients had higher CCI scores (p = 0.04).

Conclusion: Combined ERCP/EUS in one session is safe in the general population and elderly patients, with no more adverse events than in non-elderly patients.

Publication types

  • Comparative Study

MeSH terms

  • Abdominal Pain / epidemiology
  • Abdominal Pain / etiology
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Cholangiopancreatography, Endoscopic Retrograde / adverse effects*
  • Cholangitis / epidemiology
  • Cholangitis / etiology
  • Endosonography / adverse effects*
  • Female
  • Humans
  • Incidence
  • Jaundice* / diagnostic imaging
  • Male
  • Middle Aged
  • Nausea / epidemiology
  • Nausea / etiology
  • Pancreatic Neoplasms* / diagnostic imaging
  • Pancreatitis* / diagnostic imaging
  • Patient Safety*
  • Retrospective Studies