How we manage prostate biopsy and prostate cancer therapy in men with haemophilia

Haemophilia. 2012 May;18(3):e88-90. doi: 10.1111/j.1365-2516.2012.02787.x. Epub 2012 Apr 16.

Abstract

A 56-year-old African American male with severe haemophilia A [baseline factor VIII (FVIII) activity <1%] and chronic hepatitis C virus infection started annual serial monitoring of prostate-specific antigen (PSA) at age 40 because of a family history of prostate cancer (his father died from the disease at age 63). His most recent PSA level was 4.4 ng L (-1); previous values were <3 ng L(-1 . Digital rectal examination was unrevealing.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biopsy / methods*
  • Coagulants / administration & dosage*
  • Factor VIII / administration & dosage*
  • Hemophilia A / drug therapy*
  • Hemorrhage / prevention & control*
  • Humans
  • Male
  • Middle Aged
  • Prostate-Specific Antigen / blood
  • Prostatic Neoplasms / diagnosis*
  • Prostatic Neoplasms / surgery

Substances

  • Coagulants
  • Factor VIII
  • Prostate-Specific Antigen