Unexpected neuroimaging abnormalities in patients with apparent C8 radiculopathy: broadening the clinical spectrum

Muscle Nerve. 2012 Jun;45(6):859-65. doi: 10.1002/mus.23319.

Abstract

Introduction: C8-root impingement by C7/T1 lesions on neuroimaging studies is not consistently observed in C8 radiculopathy. We hypothesized that C7 or T1 root lesions (with a pre- or postfixed plexus) or cervical myelopathy might explain some "C8 radiculopathies" without C8 root compression.

Methods: Retrospective analysis of cervical neuroimaging in 31 consecutive patients with EMG-confirmed C8 radiculopathy.

Results: Five patients (16%) had C8-root compression at C7/T1. Of those without C8-root compression, 5 (16%) had C7-root compression at C6/7, one (3%) had T1-root compression at T1/T2, 7 (23%) had cervical cord compression at or above the C6/7 level, 4 (13%) had intramedullary cervical lesions, and 9 (29%) had mild or nonspecific findings.

Conclusions: C8 radiculopathy without C8-root compression may be due to C7-root compression in the setting of a "prefixed" brachial plexus, upper cervical cord compression with vascular compromise of the distal cervical spinal cord ("myelopathic hand"), or intramedullary cervical cord lesions.

MeSH terms

  • Adult
  • Cervical Vertebrae / diagnostic imaging
  • Cervical Vertebrae / pathology*
  • Cohort Studies
  • Electrodiagnosis
  • Electromyography
  • Female
  • Humans
  • Male
  • Middle Aged
  • Myelography
  • Neuroimaging / methods*
  • Radiculopathy / diagnostic imaging
  • Radiculopathy / pathology*
  • Retrospective Studies
  • Thoracic Vertebrae / diagnostic imaging
  • Thoracic Vertebrae / pathology