Vascular anomalies in pediatrics

R Dawn Fevurly; Steven J Fishman

doi:10.1016/j.suc.2012.03.016

Vascular anomalies in pediatrics

Surg Clin North Am. 2012 Jun;92(3):769-800, x. doi: 10.1016/j.suc.2012.03.016. Epub 2012 Apr 26.

Authors

R Dawn Fevurly¹, Steven J Fishman

Affiliation

¹ Department of Surgery, Vascular Anomalies Center, Children's Hospital Boston, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.

PMID: 22595720
DOI: 10.1016/j.suc.2012.03.016

Abstract

Vascular tumors consist of lesions secondary to endothelial hyperplasia, incorporating both hemangiomas and less common pediatric vascular tumors. Vascular malformations arise by dysmorphogenesis and exhibit normal endothelial cell turnover. Some anomalies may incorporate multiple areas of the vascular tree. Use of this division has provided a clinically useful method of diagnosis and prognosis, as well as a guide to therapy. It is hoped that with continued investigation into the biology and pathogenesis of these lesions, a more comprehensive molecular classification will soon be developed.

Publication types

Review

MeSH terms

Child
Diagnosis, Differential
Hemangioma* / diagnosis
Hemangioma* / etiology
Hemangioma* / therapy
Humans
Lymphangioma / diagnosis
Lymphangioma / therapy
Lymphatic Abnormalities / diagnosis
Lymphatic Abnormalities / therapy
Telangiectasis / diagnosis
Telangiectasis / therapy
Vascular Malformations* / diagnosis
Vascular Malformations* / etiology
Vascular Malformations* / therapy