Increased intravenous hydration of nulliparas in labor

Int J Gynaecol Obstet. 2012 Sep;118(3):213-5. doi: 10.1016/j.ijgo.2012.03.041. Epub 2012 Jun 18.

Abstract

Objective: To assess the effects of intravenous hydration on the duration of active labor in nulliparous women also allowed unrestricted oral consumption of fluids.

Methods: In a randomized clinical trial 120 nulliparous women with uncomplicated singleton pregnancies at term were randomly assigned to drink fluids at will and receive either no intravenous hydration (group 1) or a Ringer lactate solution at rates of 60 mL, 120 mL, or 240 mL per hour (groups 2-4) throughout active labor.

Results: There were differences in duration for the active phase of the first stage of labor (252.3 ± 40.9 min in group 1 vs 206.7±38.3 min in group 4; P<0.001) and for the second stage (64.3 ± 13.9 in group 1 vs 49.8 ± 11.4 min in group 4; P=0.01), but not for the third stage. The percentage of participants who needed labor augmentation with oxytocin was less when intravenous hydration was provided (53.3% in group 1 vs 20.0% in group 4; P=0.02).

Conclusion: Intravenous hydration significantly decreased the duration of active labor and reduced the frequency of both prolonged labor and oxytocin administration in nulliparous women. htpp://www.irct.ir registration number: IRCT201105256575N2.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Intravenous
  • Adult
  • Drinking
  • Female
  • Fluid Therapy / methods*
  • Humans
  • Isotonic Solutions / therapeutic use
  • Labor, Obstetric*
  • Oxytocics / therapeutic use
  • Oxytocin / therapeutic use
  • Parity*
  • Pregnancy
  • Rehydration Solutions / administration & dosage*
  • Ringer's Lactate
  • Young Adult

Substances

  • Isotonic Solutions
  • Oxytocics
  • Rehydration Solutions
  • Ringer's Lactate
  • Oxytocin