Phenylpropanoids from Phragmipedium calurum and their antiproliferative activity

Phytochemistry. 2012 Oct:82:172-5. doi: 10.1016/j.phytochem.2012.06.017. Epub 2012 Jul 16.

Abstract

Seven stilbenes and one alkylresorcinol were isolated from the orchid Phragmipedium calurum during a screen for anticancer compounds. They were evaluated for antiproliferative activity against multiple human cancer cell lines, and two displayed moderate activity against several cell lines.

MeSH terms

  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / isolation & purification*
  • Antineoplastic Agents / pharmacology*
  • Cell Line, Tumor
  • Cell Proliferation / drug effects
  • Humans
  • Orchidaceae / chemistry*
  • Resorcinols / chemistry
  • Resorcinols / isolation & purification*
  • Resorcinols / pharmacology*
  • Stilbenes / chemistry
  • Stilbenes / isolation & purification*
  • Stilbenes / pharmacology*

Substances

  • Antineoplastic Agents
  • Resorcinols
  • Stilbenes
  • resorcinol