Neuroleptic-induced catatonia or a mild form of neuroleptic malignant syndrome?

Neuropsychobiology. 1990;23(1):38-40. doi: 10.1159/000118713.

Abstract

Neuroleptic-induced catatonia (NIC) and milder neuroleptic malignant syndrome (NMS) share parkinsonian features, catatonic symptoms, mild fever, and have been described in patients receiving antipsychotic agents. We report the case of a patient with a schizophreniform disorder and a mild mental retardation who developed a condition which can be diagnosed either as NIC or as a mild form of NMS and has been treated successfully with a combination of amantadine (600 mg/day) and diazepam (30 mg/day). The overlapping between NIC and mild NMS cases might lead to an overestimation of the incidence of current NMS and reinforces the view of the existence of a 'neuroleptic toxicity spectrum'.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Catatonia / chemically induced*
  • Catatonia / diagnosis
  • Diagnosis, Differential
  • Haloperidol / administration & dosage
  • Haloperidol / adverse effects
  • Haloperidol / analogs & derivatives*
  • Humans
  • Injections, Intramuscular
  • Male
  • Neuroleptic Malignant Syndrome / diagnosis*
  • Psychotic Disorders / drug therapy*
  • Psychotic Disorders / psychology

Substances

  • haloperidol decanoate
  • Haloperidol