Abstract
A novel surface plasmon resonance (SPR) biosensor which is capable of monitoring proteomic biomarker secretion from living cells is reported here. Vascular endothelial growth factor (VEGF) secretion from living SKOV-3 ovarian cancer cells was measured for concept demonstration.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Biomarkers / analysis
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Biomarkers / metabolism
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Carcinoma / chemistry*
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Carcinoma / metabolism
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Carcinoma / pathology
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Cell Line, Tumor
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Female
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Humans
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Ovarian Neoplasms / chemistry*
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Ovarian Neoplasms / metabolism
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Ovarian Neoplasms / pathology
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Surface Plasmon Resonance*
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Vascular Endothelial Growth Factor A / analysis*
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Vascular Endothelial Growth Factor A / metabolism
Substances
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Biomarkers
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Vascular Endothelial Growth Factor A