[Diagnosis and treatment of trauma-induced coagulopathy]

Transfus Clin Biol. 2012 Nov;19(4-5):165-73. doi: 10.1016/j.tracli.2012.07.004. Epub 2012 Oct 4.
[Article in French]

Abstract

Trauma-induced coagulopathy is frequent and complex, and is responsible for an impairment of trauma outcome. Diagnosis of trauma coagulopathy is usually done with standard biology but recently new technics arose and gave us the opportunity to have faster information on coagulopathy with quick INR measure or clot formation study with thrombelastometry. Treatment of the coagulopathy should be done earlier in the course of trauma. Two strategies are possible that include either the association of RBC, platelet and FFP in a predefined ratio, or the use of factor concentrates guided with thrombelastometry. Treatment of favouring factors such as hypothermia, acidosis and hypocalcemia is also mandatory.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Blood Coagulation Disorders / diagnosis*
  • Blood Coagulation Disorders / etiology
  • Blood Coagulation Disorders / physiopathology
  • Blood Coagulation Disorders / therapy*
  • Blood Transfusion
  • Humans
  • Wounds and Injuries / complications*