Scalp EEG-based discrimination of cognitive deficits after traumatic brain injury using event-related Tsallis entropy analysis

IEEE Trans Biomed Eng. 2013 Jan;60(1):90-6. doi: 10.1109/TBME.2012.2223698. Epub 2012 Oct 10.

Abstract

Traumatic brain injury (TBI) is the leading cause of death and disability in children and adolescents in the U.S. This is a pilot study, which explores the discrimination of chronic TBI from normal controls using scalp EEG during a memory task. Tsallis entropies are computed for responses during an old-new memory recognition task. A support vector machine model is constructed to discriminate between normal and moderate/severe TBI individuals using Tsallis entropies as features. Numerical analyses of 30 records (15 normal and 15 TBI) show a maximum discrimination accuracy of 93% (p-value = 7.8557E-5) using four features. These results suggest the potential of scalp EEG as an efficacious method for noninvasive diagnosis of TBI.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adult
  • Brain Injuries / physiopathology*
  • Case-Control Studies
  • Cognition Disorders / diagnosis*
  • Cognition Disorders / physiopathology
  • Electroencephalography / methods*
  • Female
  • Humans
  • Male
  • Pilot Projects
  • Scalp / physiology*
  • Signal Processing, Computer-Assisted*