2-(1,3-Dioxoisoindolin-2-yl)acetic acid-N'-[(E)-4-meth-oxy-benzyl-idene]pyridine-4-carbohydrazide (2/1)

Sladjana B Novaković; Goran A Bogdanović; Shaaban K Mohamed; Mustafa R Albayati; Ayad S Hameed

doi:10.1107/S1600536812038032

2-(1,3-Dioxoisoindolin-2-yl)acetic acid-N'-[(E)-4-meth-oxy-benzyl-idene]pyridine-4-carbohydrazide (2/1)

Acta Crystallogr Sect E Struct Rep Online. 2012 Oct 1;68(Pt 10):o2897-8. doi: 10.1107/S1600536812038032. Epub 2012 Sep 8.

Authors

Sladjana B Novaković¹, Goran A Bogdanović, Shaaban K Mohamed, Mustafa R Albayati, Ayad S Hameed

Affiliation

¹ 'Vinča' Institute of Nuclear Sciences, Laboratory of Theoretical Physics and Condensed Matter Physics, University of Belgrade, PO Box 522, 11001 Belgrade, Serbia.

Abstract

In the crystal structure of the title compound, 2C(10)H(7)NO(4)·C(14)H(13)N(3)O(2), the two independent acid mol-ecules are connected through strong O-H⋯N and O-H⋯O hydrogen bonds to the central mol-ecule of the anti-tubercular drug N'-[(E)-4-meth-oxy-benzyl-idene]pyridine-4-carbohydrazide. Two such trimolecular units related by an inversion centre inter-act through a pair of N-H⋯O hydrogen bonds, forming a 3 + 3 mol-ecular aggregate. The dihedral angle between the aromatic rings of the hydrazone mol-ecule is 1.99 (12)°. The crystal packing features weak C-H⋯O and π-π stacking inter-actions, with centroid-centroid distances of 3.8460 (19) and 3.8703 (13) Å.