Abstract
Hemoglobin SO-Arab is a rare sickling disorder with a clinical course similar to that of hemoglobin SS. Hemoglobin C-Harlem is another rare condition that produces sickling disorders in affected individuals with a disease course and electrophoretic findings similar to that of hemoglobin SO-Arab. The authors report the case of a 38-year-old African American man with hemoglobin SO-Arab and the challenges that may arise in working up a rare hemoglobinopathy.
MeSH terms
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Adult
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Anemia, Sickle Cell / diagnosis*
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Anemia, Sickle Cell / genetics
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Anemia, Sickle Cell / metabolism
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Black or African American
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Chromatography, High Pressure Liquid / methods
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Electrophoresis / methods
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Genetic Techniques
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Hemoglobin, Sickle* / analysis
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Hemoglobins, Abnormal* / analysis
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Heterozygote
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Humans
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Louisiana
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Male
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alpha-Thalassemia / diagnosis*
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alpha-Thalassemia / genetics
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alpha-Thalassemia / metabolism
Substances
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Hemoglobin, Sickle
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Hemoglobins, Abnormal
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hemoglobin Arab