Perceptions on the effectiveness of treatment and the timeline of Buruli ulcer influence pre-hospital delay reported by healthy individuals

PLoS Negl Trop Dis. 2013;7(1):e2014. doi: 10.1371/journal.pntd.0002014. Epub 2013 Jan 17.

Abstract

Background: Delay in seeking treatment at the hospital is a major challenge in current Buruli ulcer control; it is associated with severe sequelae and functional limitations. Choosing alternative treatment and psychological, social and practical factors appear to influence delay. Objectives were to determine potential predictors for pre-hospital delay with Leventhal's commonsense model of illness representations, and to explore whether the type of available dominant treatment modality influenced individuals' perceptions about BU, and therefore, influenced pre-hospital delay.

Methodology: 130 healthy individuals aged >18 years, living in BU-endemic areas in Benin without any history of BU were included in this cross-sectional study. Sixty four participants from areas where surgery was the dominant treatment and sixty six participants from areas where antibiotic treatment was the dominant treatment modality were recruited. Using a semi-structured interview we measured illness perceptions (IPQ-R), knowledge about BU, background variables and estimated pre-hospital delay.

Principal findings: The individual characteristics 'effectiveness of treatment' and 'timeline acute-chronic' showed the strongest association with pre-hospital delay. No differences were found between regions where surgery was the dominant treatment and regions where antibiotics were the dominant treatment modality.

Conclusions: Individual characteristics, not anticipated treatment modality appeared predictors of pre-hospital delay.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Benin
  • Buruli Ulcer / drug therapy*
  • Buruli Ulcer / surgery*
  • Cross-Sectional Studies
  • Female
  • Health Knowledge, Attitudes, Practice*
  • Humans
  • Interviews as Topic
  • Male
  • Middle Aged
  • Patient Acceptance of Health Care*
  • Time Factors
  • Young Adult

Grants and funding

This work was supported by the Buruli Ulcer Groningen Foundation, the Groningen University Fund, the Marco Polo fund (to MA) and the Dutch Organization for Scientific Research (VENI grant to YS). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.