Rare variations in IL36RN in severe adverse drug reactions manifesting as acute generalized exanthematous pustulosis

J Invest Dermatol. 2013 Jul;133(7):1904-7. doi: 10.1038/jid.2013.44. Epub 2013 Jan 28.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Generalized Exanthematous Pustulosis / classification
  • Acute Generalized Exanthematous Pustulosis / genetics*
  • Aged, 80 and over
  • Amoxicillin / adverse effects
  • Clindamycin / adverse effects
  • Drug-Related Side Effects and Adverse Reactions / genetics*
  • Female
  • Genetic Variation / genetics*
  • Heterozygote
  • Homozygote
  • Humans
  • Interleukins / genetics*
  • Male
  • Middle Aged
  • Mutation, Missense / genetics*
  • Piroxicam / adverse effects
  • Signal Transduction / physiology

Substances

  • IL36RN protein, human
  • Interleukins
  • Piroxicam
  • Clindamycin
  • Amoxicillin