Managing data for the international, multicentre INTERGROWTH-21st Project

E O Ohuma; L Hoch; C Cosgrove; H E Knight; L Cheikh Ismail; L Juodvirsiene; A T Papageorghiou; H Al-Jabri; M Domingues; P Gilli; N Kunnawar; N Musee; F Roseman; A Carter; M Wu; D G Altman; International Fetal and Newborn Growth Consortium for the 21st Century

doi:10.1111/1471-0528.12080

Managing data for the international, multicentre INTERGROWTH-21st Project

BJOG. 2013 Sep:120 Suppl 2:64-70, v. doi: 10.1111/1471-0528.12080. Epub 2013 May 17.

Authors

E O Ohuma¹, L Hoch, C Cosgrove, H E Knight, L Cheikh Ismail, L Juodvirsiene, A T Papageorghiou, H Al-Jabri, M Domingues, P Gilli, N Kunnawar, N Musee, F Roseman, A Carter, M Wu, D G Altman; International Fetal and Newborn Growth Consortium for the 21st Century

Collaborators

International Fetal and Newborn Growth Consortium for the 21st Century:
M Katz, M K Bhan, C Garza, S Zaidi, A Langer, P M Rothwell, D Weatherall, Z A Bhutta, J Villar, S Kennedy, D G Altman, F C Barros, E Bertino, F Burton, M Carvalho, L Cheikh Ismail, W C Chumlea, M G Gravett, Y A Jaffer, A Lambert, P Lumbiganon, J A Noble, R Y Pang, A T Papageorghiou, M Purwar, J Rivera, C Victora, J Villar, D G Altman, Z A Bhutta, L Cheikh Ismail, S Kennedy, A Lambert, J A Noble, A T Papageorghiou, J Villar, S Kennedy, L Cheikh Ismail, A Lambert, A T Papageorghiou, M Shorten, L Hoch, H E Knight, E O Ohuma, C Cosgrove, I Blakey, D G Altman, F Roseman, N Kunnawar, S H Gu, J H Wang, M H Wu, M Domingues, P Gilli, L Juodvirsiene, L Hoch, N Musee, H Al-Jabri, S Waller, C Cosgrove, D Muninzwa, E O Ohuma, D Yellappan, A Carter, D Reade, R Miller, A T Papageorghiou, L Salomon, A Leston, A Mitidieri, F Al-Aamri, W Paulsene, J Sande, W K S Al-Zadjali, C Batiuk, S Bornemeier, M Carvalho, M Dighe, P Gaglioti, N Jacinta, S Jaiswal, J A Noble, K Oas, M Oberto, E Olearo, M G Owende, J Shah, S Sohoni, T Todros, M Venkataraman, S Vinayak, L Wang, D Wilson, Q Q Wu, S Zaidi, Y Zhang, P Chamberlain, D Danelon, I Sarris, J Dhami, C Ioannou, C L Knight, R Napolitano, C Pace, V Mkrtychyan, L Cheikh Ismail, W C Chumlea, F Al-Habsi, Z A Bhutta, A Carter, M Alija, J M Jimenez-Bustos, J Kizidio, F Puglia, N Kunnawar, H Liu, S Lloyd, D Mota, R Ochieng, C Rossi, M Sanchez Luna, Y J Shen, H E Knight, D A Rocco, I O Frederick, Z A Bhutta, E Albernaz, M Batra, B A Bhat, E Bertino, P Di Nicola, F Giuliani, I Rovelli, K McCormick, R Ochieng, R Y Pang, V Paul, V Rajan, A Wilkinson, A Varalda, B Eskenazi, L A Corra, H Dolk, J Golding, A Matijasevich, T de Wet, J J Zhang, A Bradman, D Finkton, O Burnham, F Farhi, F C Barros, M Domingues, S Fonseca, A Leston, A Mitidieri, D Mota, I K Sclowitz, M F da Silveira, R Y Pang, Y P He, Y Pan, Y J Shen, M H Wu, Q Q Wu, J H Wang, Y Yuan, Y Zhang, M Purwar, A Choudhary, S Choudhary, S Deshmukh, D Dongaonkar, M Ketkar, V Khedikar, N Kunnawar, C Mahorkar, I Mulik, K Saboo, C Shembekar, A Singh, V Taori, K Tayade, A Somani, E Bertino, P Di Nicola, M Frigerio, G Gilli, P Gilli, M Giolito, F Giuliani, M Oberto, L Occhi, C Rossi, I Rovelli, F Signorile, T Todros, M Carvalho, J Kizidio, R Ochieng, J Shah, W Stones, S Vinayak, N Musee, C Kisiang'ane, D Muninzwa, Y A Jaffer, J Al-Abri, J Al-Abduwani, F M Al-Habsi, H Al-Lawatiya, B Al-Rashidiya, W K S Al-Zadjali, F R Juangco, M Venkataraman, H Al-Jabri, D Yellappan, S Kennedy, L Cheikh Ismail, A T Papageorghiou, F Roseman, A Lambert, S Lloyd, R Napolitano, C Ioannou, I Sarris, M G Gravett, C Batiuk, M Batra, S Bornemeier, M Dighe, K Oas, W Paulsene, D Wilson, I O Frederick, H F Andersen, S E Abbott, A A Carter, H Algren, D A Rocco, T K Sorensen, D Enquobahrie, S Waller

Affiliation

¹ Nuffield Department of Obstetrics & Gynaecology, and, Oxford Maternal & Perinatal Health Institute, Green Templeton College, University of Oxford, Oxford, UK; Centre for Statistics in Medicine, Wolfson College Annexe, University of Oxford, Oxford, UK, UK.

PMID: 23679040
DOI: 10.1111/1471-0528.12080

Abstract

The INTERGROWTH-21(st) Project data management was structured incorporating both a centralised and decentralised system for the eight study centres, which all used the same database and standardised data collection instruments, manuals and processes. Each centre was responsible for the entry and validation of their country-specific data, which were entered onto a centralised system maintained by the Data Coordinating Unit in Oxford. A comprehensive data management system was designed to handle the very large volumes of data. It contained internal validations to prevent incorrect and inconsistent values being captured, and allowed online data entry by local Data Management Units, as well as real-time management of recruitment and data collection by the Data Coordinating Unit in Oxford. To maintain data integrity, only the Data Coordinating Unit in Oxford had access to all the eight centres' data, which were continually monitored. All queries identified were raised with the relevant local data manager for verification and correction, if necessary. The system automatically logged an audit trail of all updates to the database with the date and name of the person who made the changes. These rigorous processes ensured that the data collected in the INTERGROWTH-21(st) Project were of exceptionally high quality.

Keywords: Data management; INTERGROWTH-21st; fetal growth; standards.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Child Development*
Clinical Protocols
Cross-Sectional Studies / methods
Cross-Sectional Studies / standards
Data Collection / methods*
Data Collection / standards
Databases, Factual* / standards
Fetal Development*
Growth Charts*
Humans
Infant
Infant, Newborn / growth & development
Longitudinal Studies / methods
Longitudinal Studies / standards
Multicenter Studies as Topic / methods*
Multicenter Studies as Topic / standards
Quality Control
Research Design* / standards

Abstract

Publication types

MeSH terms

Grants and funding