viRome: an R package for the visualization and analysis of viral small RNA sequence datasets

Bioinformatics. 2013 Aug 1;29(15):1902-3. doi: 10.1093/bioinformatics/btt297. Epub 2013 May 24.

Abstract

Summary: RNA interference (RNAi) is known to play an important part in defence against viruses in a range of species. Second-generation sequencing technologies allow us to assay these systems and the small RNAs that play a key role with unprecedented depth. However, scientists need access to tools that can condense, analyse and display the resulting data. Here, we present viRome, a package for R that takes aligned sequence data and produces a range of essential plots and reports.

Availability and implementation: viRome is released under the BSD license as a package for R available for both Windows and Linux http://virome.sf.net. Additional information and a tutorial is available on the ARK-Genomics website: http://www.ark-genomics.org/bioinformatics/virome.

Contact: mick.watson@roslin.ed.ac.uk.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Computer Graphics
  • Genomics
  • RNA Interference
  • RNA, Small Untranslated / chemistry*
  • RNA, Viral / chemistry*
  • Sequence Alignment
  • Sequence Analysis, RNA
  • Software*

Substances

  • RNA, Small Untranslated
  • RNA, Viral