In the past 10 years, most medical journals have developed Web sites that not only deliver the electronic version of their publication but also provide a multimedia collection of resources, articles, educational tools, and external links to meet the needs and interests of the 21st century clinician. This article presents an evaluation tool with 5 criteria to assess the quality and scope of a medical journal's Web site and provides readers with an assessment and detailed tour through the Web sites of 5 major medical journals.