Hopping between differentiation states in lung adenocarcinoma

Cancer Cell. 2013 Jun 10;23(6):707-9. doi: 10.1016/j.ccr.2013.05.013.

Abstract

The work by Cheung and colleagues, in this issue of Cancer Cell, demonstrates another example of how lineage-specific transcriptional regulators of differentiation, GATA6 and HOPX, can control the fate of lung adenocarcinoma progression.

Publication types

  • Comment

MeSH terms

  • Adenocarcinoma / pathology*
  • Adenocarcinoma of Lung
  • GATA6 Transcription Factor / physiology*
  • Homeodomain Proteins / physiology*
  • Humans
  • Lung Neoplasms / pathology*
  • Neoplasm Metastasis / pathology*
  • Tumor Suppressor Proteins / physiology*

Substances

  • GATA6 Transcription Factor
  • GATA6 protein, human
  • HOPX protein, human
  • Homeodomain Proteins
  • Tumor Suppressor Proteins