Vascular compression of the airway: establishing a functional diagnostic algorithm

JAMA Otolaryngol Head Neck Surg. 2013 Jun;139(6):586-91. doi: 10.1001/jamaoto.2013.3214.

Abstract

Importance: Pediatric imaging carries the risk of radiation exposure. Children frequently undergo computed tomography with angiography (CTA) for findings on bronchoscopy with limited knowledge regarding the necessity of such imaging.

Objective: To report our experience with all pediatric patients at our institution over an 8-year period with airway symptoms warranting bronchoscopy followed by CTA for potential vascular anomaly. Goals were to report the percentage of positive findings seen on CTA leading to surgery; discuss relative radiation exposure risk and sedation risk for additional radiologic studies; and propose a functional diagnostic algorithm.

Design, setting, and participants: Retrospective chart review of 42 children aged 2 months to 11 years with tracheomalacia who underwent CTA between 2004 and 2012 in our tertiary aerodigestive center.

Interventions: Bronchoscopy and CTA.

Main outcomes and measures: Presence of vascular anomaly and need for thoracic surgery.

Results: Of these 42 children, 21 (50%) had a vascular anomaly identified on CTA. Of these 21, 17 (81%) had innominate artery compression; 1 (5%) had double aortic arch; 1 (5%) had right aortic arch; 3 (14%) had bronchial compression by pulmonary artery; and 1 (5%) had dextrocardia with duplicated vena cava. Six (29%) of these 21 had clinical symptoms and CTA findings requiring thoracic surgery. The most common symptoms in children requiring thoracic surgery were cough, cyanosis, and stridor.

Conclusions and relevance: Deciding when to obtain imaging for bronchoscopic findings suggestive of vascular compression remains challenging. A diagnostic algorithm is proposed as a means to provide the best clinical care while weighing risks of additional radiation exposure vs sedation and exposure to general anesthesia.

MeSH terms

  • Algorithms*
  • Angiography
  • Bronchoscopy
  • Child
  • Child, Preschool
  • Diagnosis, Differential
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Retrospective Studies
  • Tomography, X-Ray Computed
  • Tracheomalacia / diagnosis*
  • Tracheomalacia / etiology*
  • Tracheomalacia / surgery
  • Vascular Malformations / complications*
  • Vascular Malformations / diagnosis*
  • Vascular Malformations / surgery