Cancer concepts and principles: primer for the interventional oncologist-part II

Abstract

This is the second of a two-part overview of the fundamentals of oncology for interventional radiologists. The first part focused on clinical trials, basic statistics, assessment of response, and overall concepts in oncology. This second part aims to review the methods of tumor characterization; principles of the oncology specialties, including medical, surgical, radiation, and interventional oncology; and current treatment paradigms for the most common cancers encountered in interventional oncology, along with the levels of evidence that guide these treatments.

Keywords: 5-FU; 5-fluorouracil; AFP; AJCC; American Joint Committee on Cancer; BCLC; Barcelona Clinic Liver Cancer; CRC; CapeOx; DEB; DEBIRI; EASL; EGFR; European Association for Study of the Liver; FOLFIRI; FOLFOX; HCC; IRE; NCCN; NCI; NET; NSCLC; National Cancer Institute; National Comprehensive Cancer Network; PV; RF; RT; VEGFR; capecitabine/oxaliplatin; colorectal cancer; drug-eluting bead; drug-eluting beads with irinotecan; epidermal growth factor receptor; hepatocellular carcinoma; irinotecan/5-fluorouracil/leucovorin; irreversible electroporation; neuroendocrine tumor; non–small-cell lung cancer; oxaliplatin/5-fluorouracil/leucovorin; portal vein; radiation therapy; radiofrequency; vascular endothelial growth factor receptor; α-fetoprotein.