Abstract
Quetiapine is an atypical antipsychotic with known α-adrenergic antagonism. We present a case of refractory hypotension that occurred after induction of general anesthesia in a patient being treated with quetiapine. This patient was not currently taking antihypertensives and had no known cardiovascular abnormalities. We observed that the hypotension was most responsive to vasopressin. We recommend further investigation regarding the interaction of quetiapine and general anesthesia.
MeSH terms
-
Adult
-
Anesthesia, General / adverse effects*
-
Antidepressive Agents, Second-Generation / adverse effects
-
Antidepressive Agents, Second-Generation / therapeutic use
-
Antimanic Agents / adverse effects
-
Antimanic Agents / therapeutic use
-
Antipsychotic Agents / adverse effects*
-
Blood Pressure / drug effects
-
Carbon Dioxide / blood
-
Cardiac Surgical Procedures
-
Cyclohexanols / adverse effects
-
Cyclohexanols / therapeutic use
-
Dibenzothiazepines / adverse effects*
-
Electronic Health Records
-
Ephedrine / therapeutic use
-
Female
-
Humans
-
Hypotension / chemically induced*
-
Hypotension / drug therapy
-
Intraoperative Complications / chemically induced*
-
Intraoperative Complications / drug therapy
-
Lamotrigine
-
Obesity, Morbid
-
Operating Rooms
-
Oxygen / blood
-
Phenylephrine / therapeutic use
-
Quetiapine Fumarate
-
Triazines / adverse effects
-
Triazines / therapeutic use
-
Vasoconstrictor Agents / therapeutic use
-
Vasopressins / therapeutic use
-
Venlafaxine Hydrochloride
Substances
-
Antidepressive Agents, Second-Generation
-
Antimanic Agents
-
Antipsychotic Agents
-
Cyclohexanols
-
Dibenzothiazepines
-
Triazines
-
Vasoconstrictor Agents
-
Vasopressins
-
Carbon Dioxide
-
Phenylephrine
-
Quetiapine Fumarate
-
Venlafaxine Hydrochloride
-
Ephedrine
-
Oxygen
-
Lamotrigine