Anti-inflammatory and antioxidative effects of a methanol extract from bulbs of Scilla scilloides

Biosci Biotechnol Biochem. 2013;77(7):1569-71. doi: 10.1271/bbb.120906.

Abstract

The extract from bulbs of Scilla scilloides exhibited inhibitory effects in lipoxygenase and hyaluronidase assays and various oxidation models in vitro. Incubating the cells in the presence of this extract ameliorated t-butyl hydroperoxide-induced cytotoxicity from 27% to 57% in a macrophage model. The results may indicate the potential role of S. scilloides for its anti-inflammatory and antioxidative effects.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anti-Inflammatory Agents / isolation & purification
  • Anti-Inflammatory Agents / pharmacology*
  • Antioxidants / isolation & purification
  • Antioxidants / pharmacology*
  • Cell Line
  • Macrophages / metabolism
  • Methanol / chemistry*
  • Mice
  • Oxidative Stress / drug effects
  • Plant Stems / chemistry*
  • Scilla / chemistry*

Substances

  • Anti-Inflammatory Agents
  • Antioxidants
  • Methanol