Fatal rhabdomyolysis as a complication of bone marrow transplantation

L Volin; G Järventie; T Ruutu

Fatal rhabdomyolysis as a complication of bone marrow transplantation

Bone Marrow Transplant. 1990 Jul;6(1):59-60.

Authors

L Volin¹, G Järventie, T Ruutu

Affiliation

¹ Third Department of Medicine, Helsinki University Central Hospital, Finland.

PMID: 2390634

Abstract

We describe fatal rhabdomyolysis in a 24-year-old man who had received a bone marrow transplant from a sibling for the treatment of chronic granulocytic leukaemia. The rhabdomyolysis was preceded by a grand mal seizure probably caused by a combination of cyclosporin A and corticosteroids given for the prevention and treatment of acute graft-versus-host disease.

Publication types

Case Reports

MeSH terms

Acute Disease
Adrenal Cortex Hormones / adverse effects
Adult
Bone Marrow Transplantation / adverse effects*
Cyclosporins / adverse effects
Graft vs Host Disease / drug therapy
Humans
Ketoconazole / adverse effects
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / drug therapy
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / surgery
Male
Rhabdomyolysis / etiology*
Seizures / etiology

Substances

Adrenal Cortex Hormones
Cyclosporins
Ketoconazole